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Comparative Study
. 2016 Feb;160(4):525-9.
doi: 10.1007/s10517-016-3212-x. Epub 2016 Feb 22.

Variability of the Phenotype and Proliferation and Migration Characteristics of Human Mesenchymal Stromal Cells Derived from the Deciduous Teeth Pulp of Different Donors

I V Vakhrushev  1 , A S Vdovin  2 , L A Strukova  3 , K N Yarygin  2
Affiliations
Comparative Study

Variability of the Phenotype and Proliferation and Migration Characteristics of Human Mesenchymal Stromal Cells Derived from the Deciduous Teeth Pulp of Different Donors

I V Vakhrushev et al. Bull Exp Biol Med. 2016 Feb.

Abstract

We performed a comparative study of cell phenotype and proliferation and migration activities in vitro of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies.

Keywords: SHED cells; dental pulp; mesenchymal stromal cells; tissue engineering.

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