Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Oct-Dec;16(4):125-30.
doi: 10.4103/1995-705X.172193.

The Gulf Implantable Cardioverter-defibrillator Registry: Rationale, Methodology, and Implementation

Alawi A Alsheikh-Ali  1 , Ahmad S Hersi  2 , Adel K S Hamad  3 , Ahmed R Al Fagih  4 , Faisal M Al-Samadi  5 , Abdulmohsen M Almusaad  6 , Fayez A Bokhari  7 , Fawzia Al-Kandari  8 , Bandar S Al-Ghamdi  9 , Najib Al Rawahi  10 , Nidal Asaad  11 , Salem Alkaabi  12 , Amin Daoulah  13 , Hosam A Zaky  14 , Omer Elhag  15 , Yahya S Al Hebaishi  4 , Raed Sweidan  7 , Haitham Alanazi  6 , David Chase  10 , Hani Sabbour  15 , Mohammad Al Meheiri  15 , Ismail Al Abri  10 , Mohammad Amin  3 , Khaled Dagriri  4 , Adil O Ahmed  4 , Azam Shafquat  9 , Shahul Hameed Khan  11
Affiliations

The Gulf Implantable Cardioverter-defibrillator Registry: Rationale, Methodology, and Implementation

Alawi A Alsheikh-Ali et al. Heart Views. 2015 Oct-Dec.

Abstract

Background: The implantable cardioverter-defibrillator (ICD) is effective in the prevention of sudden cardiac death in high-risk patients. Little is known about ICD use in the Arabian Gulf. We designed a study to describe the characteristics and outcomes of patients receiving ICDs in the Arab Gulf region.

Methods: Gulf ICD is a prospective, multi-center, multinational, and observational study. All adult patients 18 years or older, receiving a de novo ICD implant and willing to sign a consent form will be eligible. Data on baseline characteristics, ICD indication, procedure and programing, in-hospital, and 1-year outcomes will be collected. Target enrollment is 1500 patients, which will provide adequate precision across a wide range of expected event rates.

Results: Fifteen centers in six countries are enrolling patients (Saudi Arabia, United Arab Emirates, Kuwait, Oman, Bahrain, and Qatar). Two-thirds of the centers have dedicated electrophysiology laboratories, and in almost all centers ICDs are implanted exclusively by electrophysiologists. Nearly three-quarters of the centers reported annual ICD implant volumes of ≤150 devices, and pulse generator replacements constitute <30% of implants in the majority of centers. Enrollment started in December 2013, and accrual rate increased as more centers entered the study reaching an average of 98 patients per month.

Conclusions: Gulf ICD is the first prospective, observational, multi-center, and multinational study of the characteristics and, the outcomes of patients receiving ICDs in the Arab Gulf region. The study will provide valuable insights into the utilization of and outcomes related to ICD therapy in the Gulf region.

Keywords: Arabian Gulf; implantable defibrillator; registry.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Sample size estimation for Gulf cardioverter-defibrillator
See this image and copyright information in PMC

References

    1. Epstein AE, DiMarco JP, Ellenbogen, KA, Estes NA, 3rd, Freedman RA, Gettes LS, et al. ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2008;51:e1–62. - PubMed
    1. Epstein AE, DiMarco JP, Ellenbogen, KA, Estes NA, 3rd, Freedman RA, Gettes LS, et al. 2012 ACC/AHA/HRS Focused Update Incorporated into the ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2013;61:e6–75. - PubMed
    1. Daoulah A, Alsheikh-Ali AA, Ocheltree AH, Ocheltree S, Al-Kaabi S, Malik M, et al. Outcome after implantable cardioverter-defibrillator in patients with Brugada syndrome: The Gulf Brugada syndrome registry. J Electrocardiol. 2012;45:327–32. - PubMed
    1. Hersi AS. Implantable Cardioverter Defibrillator Therapy: A Single Center Experience in Saudi Arabia [Abstract] The Open Cardiovascular Medicine Journal. 2010;4:92. - PMC - PubMed
    1. Alsheikh-Ali AA, Alkaabi S, Elhag O, Mahmud R, Rasheed A, Al-Kasser M, et al. The implantable cardioverter-defibrillator in the united arab emirates: Preliminary findings of a national survey [Abstract] Circulation. 2012;125:515.