Response to Dr Fried & Dr Kievit, and Dr Malhi et al

L Schmaal¹, D J Veltman¹, T G M van Erp², P G Sämann³, T Frodl^{4

5}, N Jahanshad⁶, E Loehrer⁷, M W Vernooij^{8

9}, W J Niessen^{9

10

11}, M A Ikram^{8

9

12}, K Wittfeld¹³, H J Grabe^{13

14

15}, A Block¹⁴, K Hegenscheid¹⁶, D Hoehn³, M Czisch³, J Lagopoulos¹⁷, S N Hatton¹⁷, I B Hickie¹⁷, R Goya-Maldonado¹⁸, B Krämer¹⁸, O Gruber¹⁹, B Couvy-Duchesne^{20

21

22}, M E Rentería²³, L T Strike²⁰, M J Wright^{20

21}, G I de Zubicaray²⁴, K L McMahon²¹, S E Medland²⁵, N A Gillespie²⁶, G B Hall^{27

28}, L S van Velzen¹, M-J van Tol²⁹, N J van der Wee^{30

31}, I M Veer³², H Walter³², E Schramm^{33

34}, C Normann³³, D Schoepf³⁵, C Konrad^{36

37}, B Zurowski³⁸, A M McIntosh^{39

40}, H C Whalley³⁹, J E Sussmann³⁹, B R Godlewska⁴¹, F H Fischer^{42

43}, B W J H Penninx¹, P M Thompson⁶, D P Hibar⁶

Affiliations

¹ Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
² Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA.
³ Max Planck Institute of Psychiatry, Neuroimaging Research Group, Munich, Germany.
⁴ Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Magdeburg, Germany.
⁵ Department of Psychiatry, Trinity College, University of Dublin, Dublin, Ireland.
⁶ Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
⁷ Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MS, USA.
⁸ Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
⁹ Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹⁰ Department of Medical Informatics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹¹ Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands.
¹² Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹³ German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Germany.
¹⁴ Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
¹⁵ Helios Hospital Stralsund, Stralsund, Germany.
¹⁶ Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
¹⁷ Clinical Research Unit, Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.
¹⁸ Center for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center (UMG), Gerog-August-University, Goettingen, Germany.
¹⁹ Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.
²⁰ Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
²¹ Center for Advanced Imaging, The University of Queensland, Brisbane, QLD, Australia.
²² Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²³ Department of Genetic Epidemiology, Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²⁴ Faculty of Health, The Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD, Australia.
²⁵ Department of Quantitative Genetics, Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²⁶ Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
²⁷ Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.
²⁸ Imaging Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
²⁹ University of Groningen, University Medical Center Groningen, Department of Neuroscience, Neuroimaging Center, Groningen, The Netherlands.
³⁰ Department of Psychiatry, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
³¹ Leiden Institute for Brain and Cognition, Leiden, The Netherlands.
³² Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.
³³ Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.
³⁴ Psychiatric University Clinic, Basel, Switzerland.
³⁵ Department of Psychiatry, University of Bonn, Bonn, Germany.
³⁶ Department of Psychiatry and Psychotherapy, Agaplesion Diakoniklinikum, Rotenburg, Germany.
³⁷ Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
³⁸ Center for Integrative Psychiatry, University of Lübeck, Lübeck, Germany.
³⁹ Division of Psychiatry, University of Edinburgh, UK.
⁴⁰ Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK.
⁴¹ Department of Psychiatry, Warneford Hospital, Oxford, UK.
⁴² Department of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité Universitätsmedizin, Berlin, Germany.
⁴³ Institute for Social Medicine, Epidemology and Health Economics, Charité Universitätsmedizin, Berlin, Germany.

PMID: 26903270
PMCID: PMC4876636
DOI: 10.1038/mp.2016.9

Comment

Response to Dr Fried & Dr Kievit, and Dr Malhi et al

L Schmaal et al. Mol Psychiatry. 2016 Jun.

. 2016 Jun;21(6):726-8.

doi: 10.1038/mp.2016.9. Epub 2016 Feb 23.

Authors

Affiliations

¹ Department of Psychiatry and Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
² Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA.
³ Max Planck Institute of Psychiatry, Neuroimaging Research Group, Munich, Germany.
⁴ Department of Psychiatry and Psychotherapy, Otto von Guericke University of Magdeburg, Magdeburg, Germany.
⁵ Department of Psychiatry, Trinity College, University of Dublin, Dublin, Ireland.
⁶ Imaging Genetics Center, Department of Neurology, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
⁷ Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MS, USA.
⁸ Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
⁹ Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹⁰ Department of Medical Informatics, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹¹ Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands.
¹² Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
¹³ German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Germany.
¹⁴ Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
¹⁵ Helios Hospital Stralsund, Stralsund, Germany.
¹⁶ Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
¹⁷ Clinical Research Unit, Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.
¹⁸ Center for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center (UMG), Gerog-August-University, Goettingen, Germany.
¹⁹ Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University Hospital, Heidelberg, Germany.
²⁰ Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
²¹ Center for Advanced Imaging, The University of Queensland, Brisbane, QLD, Australia.
²² Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²³ Department of Genetic Epidemiology, Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²⁴ Faculty of Health, The Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, QLD, Australia.
²⁵ Department of Quantitative Genetics, Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
²⁶ Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
²⁷ Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.
²⁸ Imaging Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
²⁹ University of Groningen, University Medical Center Groningen, Department of Neuroscience, Neuroimaging Center, Groningen, The Netherlands.
³⁰ Department of Psychiatry, Leiden University Medical Center, Leiden University, Leiden, The Netherlands.
³¹ Leiden Institute for Brain and Cognition, Leiden, The Netherlands.
³² Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.
³³ Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.
³⁴ Psychiatric University Clinic, Basel, Switzerland.
³⁵ Department of Psychiatry, University of Bonn, Bonn, Germany.
³⁶ Department of Psychiatry and Psychotherapy, Agaplesion Diakoniklinikum, Rotenburg, Germany.
³⁷ Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany.
³⁸ Center for Integrative Psychiatry, University of Lübeck, Lübeck, Germany.
³⁹ Division of Psychiatry, University of Edinburgh, UK.
⁴⁰ Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK.
⁴¹ Department of Psychiatry, Warneford Hospital, Oxford, UK.
⁴² Department of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité Universitätsmedizin, Berlin, Germany.
⁴³ Institute for Social Medicine, Epidemology and Health Economics, Charité Universitätsmedizin, Berlin, Germany.

PMID: 26903270
PMCID: PMC4876636
DOI: 10.1038/mp.2016.9

No abstract available

PubMed Disclaimer

Comment on

Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group.
Schmaal L, Veltman DJ, van Erp TG, Sämann PG, Frodl T, Jahanshad N, Loehrer E, Tiemeier H, Hofman A, Niessen WJ, Vernooij MW, Ikram MA, Wittfeld K, Grabe HJ, Block A, Hegenscheid K, Völzke H, Hoehn D, Czisch M, Lagopoulos J, Hatton SN, Hickie IB, Goya-Maldonado R, Krämer B, Gruber O, Couvy-Duchesne B, Rentería ME, Strike LT, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Wright MJ, Hall GB, MacQueen GM, Frey EM, Carballedo A, van Velzen LS, van Tol MJ, van der Wee NJ, Veer IM, Walter H, Schnell K, Schramm E, Normann C, Schoepf D, Konrad C, Zurowski B, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Sussmann JE, Godlewska BR, Cowen PJ, Fischer FH, Rose M, Penninx BW, Thompson PM, Hibar DP. Schmaal L, et al. Mol Psychiatry. 2016 Jun;21(6):806-12. doi: 10.1038/mp.2015.69. Epub 2015 Jun 30. Mol Psychiatry. 2016. PMID: 26122586 Free PMC article.
The volumes of subcortical regions in depressed and healthy individuals are strikingly similar: a reinterpretation of the results by Schmaal et al.
Fried EI, Kievit RA. Fried EI, et al. Mol Psychiatry. 2016 Jun;21(6):724-5. doi: 10.1038/mp.2015.199. Epub 2015 Dec 15. Mol Psychiatry. 2016. PMID: 26666203 Free PMC article. No abstract available.
Size matters; but so does what you do with it!
Malhi GS, Das P, Outhred T. Malhi GS, et al. Mol Psychiatry. 2016 Jun;21(6):725-6. doi: 10.1038/mp.2015.200. Epub 2016 Jan 5. Mol Psychiatry. 2016. PMID: 26728567 No abstract available.

References

1. Fried EI, Kievit RA. The volumes of subcortical regions in depressed and healthy individuals are strikingly similar: a reinterpretation of the results by Schmaal et al. Mol Psychiatry 2015; e-pub ahead of print 15 December 2015. - PMC - PubMed
1. Malhi GS, Das P, Outhred T. Size matters; but so does what you do with it!. Mol Psychiatry 2016; e-pub ahead of print 5 January 2016. - PubMed
1. Schmaal L, Veltman DJ, van Erp TGM, Sämann PG, Frodl T, Jahanshad N et al. Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group. Mol Psychiatry 2015. (this issue). - PMC - PubMed
1. van Erp TGM, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA et al. Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium. Mol Psychiatry 2015. (this issue). - PMC - PubMed
1. Frodl T, Schaub A, Banac S, Charypar M, Jäger M, Kümmler P et al. Reduced hippocampal volume correlates with executive dysfunctioning in major depression. J Psychiatry Neurosci 2006; 31: 316–325. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Response to Dr Fried & Dr Kievit, and Dr Malhi et al

Affiliations

Response to Dr Fried & Dr Kievit, and Dr Malhi et al

Authors

Affiliations

Comment on

References

Publication types

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources