High sodium chloride consumption enhances the effects of smoking but does not interact with SGK1 polymorphisms in the development of ACPA-positive status in patients with RA

Affiliations

¹ Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
² Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden.
³ Unit of Rheumatology, Department of Molecular medicine, Karolinska Institutet Hospital, Stockholm, Sweden.

Comment

Xia Jiang et al. Ann Rheum Dis. 2016 May.

. 2016 May;75(5):943-6.

doi: 10.1136/annrheumdis-2015-209009. Epub 2016 Feb 22.

¹ Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
² Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden.
³ Unit of Rheumatology, Department of Molecular medicine, Karolinska Institutet Hospital, Stockholm, Sweden.

No abstract available

Keywords: Autoantibodies; Epidemiology; Rheumatoid Arthritis.

Comment on

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Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA. Kleinewietfeld M, et al. Nature. 2013 Apr 25;496(7446):518-22. doi: 10.1038/nature11868. Epub 2013 Mar 6. Nature. 2013. PMID: 23467095 Free PMC article.