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. 2015 Dec;59(12):811-3.
doi: 10.4103/0019-5049.171577.

Perioperative management of patient with Bombay blood group undergoing mitral valve replacement

Shio Priye  1 , J Sathyanarayan  1 , S Shivaprakash  1 , Durgaprasad Reddy  1
Affiliations

Perioperative management of patient with Bombay blood group undergoing mitral valve replacement

Shio Priye et al. Indian J Anaesth. 2015 Dec.

Abstract

Bombay red blood cell phenotype is an extremely rare blood type for which patients can receive only autologous or Bombay phenotype red blood cells. We report a case of stenotic mitral valve with Bombay phenotype who underwent minimal invasive right lateral thoracotomy for the replacement of the mitral valve. A male patient from Bangladesh presented to the hospital with New York Heart Association III symptoms. His medical evaluation revealed severe mitral valve stenosis and mild aortic valve regurgitation. The patient received erythropoietin, intravenous iron succinate and folic acid tablets. Autologous blood transfusion was carried out. The mitral valve was replaced with a prosthetic valve successfully. After weaning off from cardiopulmonary bypass, heparinisation was corrected with protamine. Post-operatively, the patient received autologous red blood cells. The patient recovered after 1-day of inotropic support with adrenaline and milrinone, and diuretics and was discharged on the 5(th) post-operative day.

Keywords: Autologous blood donation; Bombay blood group; cardiac surgery.

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Conflict of interest statement

Conflict of Interest: None declared

References

    1. Khan MQ. Bombay blood group: A case report. Pac J Sci Technol. 2009;10:333–7.
    1. Oriol R, Candelier JJ, Mollicone R. Molecular genetics of H. Vox Sang. 2000;78(Suppl 2):105–8. - PubMed
    1. Reid ME, Westhoff CM. Human blood group antigens and antibodies. In: Hoffman R, Furie B, Benz EJ Jr, editors. Hematology: Basic Principles and Practice. 5th ed. Philadelphia: Churchill Livingston; 2008. pp. 2163–78.
    1. Chowdhury FS, Siddiqui MA, Rahman KG, Nasreen Z, Begum HA, Begum HA. A rare and clinically important blood Group - Bombay blood group. Bangladesh J Med. 2011;22:21–3.
    1. Cooling LL, Kelly K, Barton J, Hwang D, Koerner TA, Olson JD. Determinants of ABH expression on human blood platelets. Blood. 2005;105:3356–64. - PubMed