Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Feb 22;21(2):247.
doi: 10.3390/molecules21020247.

Chemistry and Pharmacology of Citrus sinensis

Juan Manuel J Favela-Hernández  1 , Omar González-Santiago  2 , Mónica A Ramírez-Cabrera  3 , Patricia C Esquivel-Ferriño  4 , María del Rayo Camacho-Corona  5
Affiliations
Review

Chemistry and Pharmacology of Citrus sinensis

Juan Manuel J Favela-Hernández et al. Molecules. .

Abstract

Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found to have beneficial properties. The present study is a review of the chemistry and pharmacology of Citrus sinensis. This review reveals the therapeutic potential of C. sinensis as a source of natural compounds with important activities that are beneficial for human health that could be used to develop new drugs.

Keywords: Citrus sinensis; chemistry; natural products; orange; pharmacological activities.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structures of flavonoids.
Figure 1
Figure 1
Chemical structures of flavonoids.
Figure 1
Figure 1
Chemical structures of flavonoids.
Figure 1
Figure 1
Chemical structures of flavonoids.
Figure 2
Figure 2
Chemical structures of steroids.
Figure 3
Figure 3
Chemical structures of hydroxyamides, alkanes and fatty acids.
Figure 4
Figure 4
Chemical structures of coumarins.
Figure 5
Figure 5
Chemical structures of peptides.
Figure 6
Figure 6
Chemical structures of carbohydrates.
Figure 7
Figure 7
Chemical structures of carbamates and alkylamines.
Figure 8
Figure 8
Chemical structures of carotenoids.
Figure 9
Figure 9
Chemical structures of volatile compounds.
Figure 9
Figure 9
Chemical structures of volatile compounds.
Figure 9
Figure 9
Chemical structures of volatile compounds.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lahlou M. The Success of Natural Products in Drug Discovery. Pharmacol. Pharm. 2013;4:17–31. doi: 10.4236/pp.2013.43A003. - DOI
    1. Moore G.A. Oranges and lemons: Clues to the taxonomy of Citrus from molecular markers. Trends Genet. 2001;17:536–540. doi: 10.1016/S0168-9525(01)02442-8. - DOI - PubMed
    1. Abbate L., Tusa N., del Bosco S.F., Strano T., Renda A., Ruberto G. Genetic improvement of Citrus fruits: New somatic hybrids from Citrus sinensis (L.) Osb. and Citrus limon (L.) Burm F. Food Res. Int. 2012;48:284–290. doi: 10.1016/j.foodres.2012.04.007. - DOI
    1. Barkley N.A., Roose M.L., Krueger R.R., Federici C.T. Assessing genetic diversity and population structure in a citrus germplasm collection utilizing simple sequence repeat markers (SSRs) Theor. Appl. Genet. 2006;112:1519–1531. doi: 10.1007/s00122-006-0255-9. - DOI - PubMed
    1. Flamini G., Cioni P.L., Morelli I. Use of solid-phase micro-extraction as a sampling technique in the determination of volatiles emitted by flowers, isolated flower parts and pollen. J. Chromatogr. A. 2003;998:229–233. doi: 10.1016/S0021-9673(03)00641-1. - DOI - PubMed

Substances

LinkOut - more resources