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Clinical Trial
. 2017 Feb;32(1):6-12.
doi: 10.1177/0268355516630154. Epub 2016 Jul 9.

ClariVein® - Early results from a large single-centre series of mechanochemical endovenous ablation for varicose veins

T Y Tang  1 , J W Kam  2 , M E Gaunt  3
Affiliations
Clinical Trial

ClariVein® - Early results from a large single-centre series of mechanochemical endovenous ablation for varicose veins

T Y Tang et al. Phlebology. 2017 Feb.

Abstract

Objectives This study assessed the effectiveness and patient experience of the ClariVein® endovenous occlusion catheter for varicose veins from a large single-centre series in the UK. Methods A total of 300 patients (371 legs) underwent ClariVein® treatment for their varicose veins; 184 for great saphenous vein (GSV) incompetence, 62 bilateral GSV, 23 short saphenous vein (SSV), 6 bilateral SSV and 25 combined unilateral great saphenous vein and SSV. Patients were reviewed at an interval of two months post procedure and underwent Duplex ultrasound assessment. Postoperative complications were recorded along with patient satisfaction. Results All 393 procedures were completed successfully under local anaesthetic. Complete occlusion of the treated vein was initially achieved in all the patients, but at eight weeks' follow-up, there was only partial obliteration in 13/393 (3.3%) veins. These were all successfully treated with ultrasound-guided foam sclerotherapy. Procedures were well tolerated with a mean pain score of 0.8 (0-10). No significant complications were reported. Conclusions ClariVein® can be used to ablate long and short saphenous varicose veins on a walk-in-walk-out basis. Bilateral procedures can be successfully performed, and these are well tolerated as can multiple veins in the same leg. Early results are promising but further evaluation and longer term follow-up are required.

Keywords: ClariVein®; endovenous; mechanochemical ablation; varicose veins.

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Figures

Figure 1.
Figure 1.
ClariVein® procedures performed. SSV: short saphenous vein; GSV: great saphenous vein.
Figure 2.
Figure 2.
ClariVein® outcome by complication and occlusion rate. SSV: short saphenous vein; GSV: great saphenous vein.
See this image and copyright information in PMC

References

    1. Kanwar A, Hansrani M, Lees T, et al. Trends in varicose vein therapy in England: radical changes in the last decade. Ann R Coll Surg Engl 2010; 92: 341–346. - PMC - PubMed
    1. Marsden G, Perry M, Kelley K, et al. Diagnosis and management of varicose veins in the legs: summary of NICE guidance. BMJ 2013; 347: f4279–f4279. - PubMed
    1. Siribumrungwong B, Noorit P, Wilasrusmee C, et al. A systematic review and meta-analysis of randomised controlled trials comparing endovenous ablation and surgical intervention in patients with varicose vein. Eur J Vasc Endovasc Surg 2012; 44: 214–223. - PubMed
    1. Sichlau MJ, Ryu RK. Cutaneous thermal injury after endovenous laser ablation of the great saphenous vein. J Vasc Interv Radiol 2004; 15: 865–867. - PubMed
    1. Van Den Bos RR, Neumann M, De Roos KP, et al. Endovenous laser ablation-induced complications: review of the literature and new cases. Dermatol Surg 2009; 35: 1206–1214. - PubMed

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