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Editorial
. 2016 Sep 15;214(6):825-7.
doi: 10.1093/infdis/jiw068. Epub 2016 Feb 16.

Dengue Vaccine: The Need, the Challenges, and Progress

Alan L Rothman  1 , Francis A Ennis  2
Affiliations
Editorial

Dengue Vaccine: The Need, the Challenges, and Progress

Alan L Rothman et al. J Infect Dis. .
No abstract available

Keywords: dengue; dengue vaccine; live virus vaccine; protective immunity; vaccine clinical trial.

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References

    1. Thomas SJ, Rothman AL. Trials and tribulations on the path to developing a dengue vaccine. Vaccine 2015; 33(suppl 4):D24–31. - PubMed
    1. Bhatt S, Gething PW, Brady OJ et al. . The global distribution and burden of dengue. Nature 2013; 496:504–7. - PMC - PubMed
    1. Hadinegoro SR, Arredondo-Garcia JL, Capeding MR et al. . Efficacy and long-term safety of a dengue vaccine in regions of endemic disease. New Engl J Med 2015; 373:1195–206. - PubMed
    1. Durbin AP, Kirkpatrick BD, Pierce KK, Schmidt AC, Whitehead SS. Development and clinical evaluation of multiple investigational monovalent DENV vaccines to identify components for inclusion in a live attenuated tetravalent DENV vaccine. Vaccine 2011; 29:7242–50. - PMC - PubMed
    1. Durbin AP, Kirkpatrick BD, Pierce KK et al. . A 12-month–interval dosing study in adults indicates that a single dose of the National Institutes of Allergy and Infectious Diseases tetravalent dengue vaccine induces a robust neutralizing antibody response. J Infect Dis 2016; 214:832–5. - PMC - PubMed