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. 2016 May 1;62(9):1136-1138.
doi: 10.1093/cid/ciw060. Epub 2016 Feb 11.

Norovirus Infections Occur in B-Cell-Deficient Patients

Julianne R Brown  1   2 , Kimberly Gilmour  3 , Judith Breuer  1   4
Affiliations

Norovirus Infections Occur in B-Cell-Deficient Patients

Julianne R Brown et al. Clin Infect Dis. .

Abstract

Norovirus incidence was compared between severe combined immunodeficiency children with (n = 10) and without (n = 8) B cells. 60% of B+ and 63% of B- patients developed norovirus infections therefore norovirus replication in B lymphocytes is not essential for infection.

Keywords: B cells; SCID; in vivo; norovirus.

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