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Review
. 2016 Aug;54(8):1964-74.
doi: 10.1128/JCM.00046-16. Epub 2016 Feb 24.

Expansion of Microbial Forensics

Affiliations
Review

Expansion of Microbial Forensics

Sarah E Schmedes et al. J Clin Microbiol. 2016 Aug.

Abstract

Microbial forensics has been defined as the discipline of applying scientific methods to the analysis of evidence related to bioterrorism, biocrimes, hoaxes, or the accidental release of a biological agent or toxin for attribution purposes. Over the past 15 years, technology, particularly massively parallel sequencing, and bioinformatics advances now allow the characterization of microorganisms for a variety of human forensic applications, such as human identification, body fluid characterization, postmortem interval estimation, and biocrimes involving tracking of infectious agents. Thus, microbial forensics should be more broadly described as the discipline of applying scientific methods to the analysis of microbial evidence in criminal and civil cases for investigative purposes.

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Figures

FIG 1
FIG 1
Diagram of expanded human investigative and forensic testing to include human genome and human microbiome characterization.
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References

    1. Budowle B, Schutzer SE, Einseln A, Kelley LC, Walsh AC, Smith JAL, Marrone BL, Robertson J, Campos J. 2003. Building microbial forensics as a response to bioterrorism. Science 301:1852–1853. doi: 10.1126/science.1090083. - DOI - PubMed
    1. Morse SA, Budowle B. 2006. Microbial forensics: application to bioterrorism preparedness and response. Infect Dis Clin North Am 20:455–473. doi: 10.1016/j.idc.2006.03.004. - DOI - PubMed
    1. Taylor LH, Latham SM, Woolhouse MEJ. 2001. Risk factors for human disease emergence. Philos Trans R Soc Lond B Biol Sci 356:983–989. doi: 10.1098/rstb.2001.0888. - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention. 2016. Bioterrorism agents/diseases. Centers for Disease Control and Prevention, Atlanta, GA: http://emergency.cdc.gov/agent/agentlist.asp.
    1. Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb J-F, Dougherty BA, Merrick JM, McKenney K, Sutton G, FitzHugh W, Fields C, Gocayne JD, Scott J, Shirley R, Liu L-I, Glodek A, Kelley JM, Weidman JF, Phillips CA, Spriggs T, Hedblom E, Cotton MD, Utterback TR, Hanna MC, Nguyen DT, Saudek DM, Brandon RC, Fine LD, Fritchman JL, Fuhrmann JL, Geoghagen NSM, Gnehm CL, McDonald LA, Small KV, Fraser CM, Smith HO, Venter JC. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496–512. doi: 10.1126/science.7542800. - DOI - PubMed

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