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Review
. 2016 Feb;24(1):275-8.
doi: 10.7534/j.issn.1009-2137.2016.01.053.

[Research Advances on Treatment of Multiple Myeloma Bone Disease--Review]

[Article in Chinese]
Zu-Yao Xia  1 , Hui-Juan Yang  1   2 , Bao-An Chen  3
Affiliations
Review

[Research Advances on Treatment of Multiple Myeloma Bone Disease--Review]

[Article in Chinese]
Zu-Yao Xia et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Feb.

Abstract

The main features of multiple myeloma bone disease (MBD) are hyperactivity of systemic bone destruction and inhibition of new bone formation. Its clinical manifestations include pain, osteoporosis, pathologic fractures and associated nerve compression symptoms etc. MBD is one of the most common complications of multiple myeloma (MM). Its misdiagnosis rate is higher, and the patients' quality of life and prognosis are poor. This review discusses the most recent advancement on its pathogenesis and novel therapies, so as to provide reference for clinical treatment of MBD.

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