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Randomized Controlled Trial
. 2016 May;84(5):389-401.
doi: 10.1037/ccp0000087. Epub 2016 Feb 25.

A randomized clinical trial of a parent-focused social-cognitive processing intervention for caregivers of children undergoing hematopoetic stem cell transplantation

Sharon Manne  1 , Laura Mee  2 , Abraham Bartell  3 , Stephen Sands  4 , Deborah A Kashy  5
Affiliations
Randomized Controlled Trial

A randomized clinical trial of a parent-focused social-cognitive processing intervention for caregivers of children undergoing hematopoetic stem cell transplantation

Sharon Manne et al. J Consult Clin Psychol. 2016 May.

Abstract

Objective: Providing care to one's child during and after a hematopoietic stem cell transplant (HSCT) is a universally stressful experience, but few psychological interventions have been developed to reduce caregiver distress. The goal of this study was to test the efficacy of a brief cognitive-behavioral intervention delivered to primary caregivers.

Method: Two hundred eighteen caregivers were assigned either best-practice psychosocial care (BPC) or a parent social-cognitive intervention program (P-SCIP). The 5 session P-SCIP was delivered during the HSCT hospitalization. Caregivers completed measures of distress, optimism, coping, and fear appraisals preintervention, 1, 6 months, and 1 year.

Results: P-SCIP reduced caregiver's distress significantly more than BPC between the pretransplant assessment (Time 1) and 1-month follow-up assessment (Time 2). P-SCIP had a stronger effect than BPC among caregivers who began the hospitalization reporting higher depression and anxiety, and among caregivers whose children developed graft-versus-host disease (GvHD). Long-term treatment effects of P-SCIP were seen in traumatic distress among caregivers who reported higher anxiety pretransplant as well as among caregivers whose children had GvHD at HSCT discharge.

Conclusions: Screening caregivers for elevations in pretransplant anxiety and targeting interventions specifically to these caregivers, as well as targeting caregivers to children who develop GvHD, may prove beneficial.

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Figures

Figure 1
Figure 1
Flow of participants in the study. BPC = best-practice psychosocial care; P-SCIP = parent social-cognitive intervention program.
Figure 2
Figure 2
Interactions between treatment condition and time. P-SCIP = parent social-cognitive intervention program; BPC = best-practice psychosocial care.
See this image and copyright information in PMC

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