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Randomized Controlled Trial
. 2016 Mar;30(3):428-34.
doi: 10.1111/jdv.13556.

Prevalence of rosacea in the general population of Germany and Russia - The RISE study

J Tan  1   2 , H Schöfer  3 , E Araviiskaia  4 , F Audibert  5 , N Kerrouche  5 , M Berg  6 ; RISE study group
Affiliations
Randomized Controlled Trial

Prevalence of rosacea in the general population of Germany and Russia - The RISE study

J Tan et al. J Eur Acad Dermatol Venereol. 2016 Mar.

Abstract

Background: There is an unmet need for general population-based epidemiological data on rosacea based on contemporary diagnostic criteria and validated population survey methodology.

Objective: To evaluate the prevalence of rosacea in the general population of Germany and Russia.

Methods: General population screening was conducted in 9-10 cities per country to ensure adequate geographic representation. In Part I of this two-phase study, screening of a representative sample of the general population (every fifth person or every fifth door using a fixed-step procedure on a random route sample) was expedited with use of a questionnaire and algorithm based on current diagnostic criteria for rosacea. Of the subjects that screened positive in the initial phase, a randomly selected sample (every third subject) t`hen underwent diagnostic confirmation by a dermatologist in Part II.

Results: A total of 3052 and 3013 subjects (aged 18-65 years) were screened in Germany and Russia respectively. Rosacea prevalence was 12.3% [95%CI, 10.2-14.4] in Germany and 5.0% [95%CI, 2.8-7.2] in Russia. The profile of subjects with rosacea (75% women; mean age of 40 years; mainly skin phototype II or III, majority of subjects with sensitive facial skin) and subtype distribution were similar. Overall, 18% of subjects diagnosed with rosacea were aged 18-30 years. Over 80% were not previously diagnosed. Within the previous year, 47.5% of subjects had received no rosacea care and 23.7% had received topical and/or systemic drugs. Over one-third (35% Germany, 43% Russia) of rosacea subjects reported a moderate to severe adverse impact on quality of life.

Conclusion: Rosacea is highly prevalent in Germany (12.3%) and Russia (5.0%). The demographic profile of rosacea subjects was similar between countries and the majority were previously undiagnosed.

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Figures

Figure 1
Figure 1
Location of the screening sites in Germany (a) and Russia (b).
Figure 2
Figure 2
Disposition of subjects in Germany and in Russia.
Figure 3
Figure 3
Rosacea care in the binational sample of 119 subjects with a confirmed diagnosis of rosacea IPL= Intense Pulsed Light.
Figure 4
Figure 4
Severity of primary (a–d) and secondary (e–h) features of rosacea in subjects with a confirmed diagnosis of rosacea. Percentages were calculated on subjects presenting the feature and several symptoms could be found in the same patient.
Figure 5
Figure 5
Effect of rosacea on quality of life (QoL) in German and Russian subjects – DLQI questionnaire.
See this image and copyright information in PMC

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