Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2016 Feb 26;351(6276):919-20.
doi: 10.1126/science.aaf2850.

IMMUNOLOGY. Maternal TH17 cells take a toll on baby's brain

Myka L Estes  1 , A Kimberley McAllister  2
Affiliations
Comment

IMMUNOLOGY. Maternal TH17 cells take a toll on baby's brain

Myka L Estes et al. Science. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1. A model for the role for Th17 cells and IL-17 in infection-induced ASD
MIA, and possibly a predisposition for autoimmunity, leads to an increase in Th17 cells in maternal serum and IL-17a, which crosses the placenta and increases IL-17 receptor levels in the brains of offspring leading to ASD-related cortical and behavioral abnormalities in offspring.
See this image and copyright information in PMC

Comment on

References

    1. Estes ML, McAllister AK. Nature Reviews Neuroscience. 2015;16:469. - PMC - PubMed
    1. Atladottir HO, et al. Journal of autism and developmental disorders. 2010;40:1423. - PubMed
    1. Atladottir HO, et al. Pediatrics. 2012;130:e1447. - PMC - PubMed
    1. Choi GB, et al. Science. 2016;XX
    1. Smith SE, Li J, Garbett K, Mirnics K, Patterson PH. J Neurosci. 2007;27:10695. - PMC - PubMed