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Review
. 2015 Nov 30:4:F1000 Faculty Rev-1373.
doi: 10.12688/f1000research.6888.1. eCollection 2015.

Necrotizing enterocolitis: controversies and challenges

Augusto Zani  1 , Agostino Pierro  1
Affiliations
Review

Necrotizing enterocolitis: controversies and challenges

Augusto Zani et al. F1000Res. .

Abstract

Necrotizing enterocolitis is a devastating intestinal disease that affects ~5% of preterm neonates. Despite advancements in neonatal care, mortality remains high (30-50%) and controversy still persists with regards to the most appropriate management of neonates with necrotizing enterocolitis. Herein, we review some controversial aspects regarding the epidemiology, imaging, medical and surgical management of necrotizing enterocolitis and we describe new emerging strategies for prevention and treatment.

Keywords: Gut; bowel; necrotizing enterocolitis.

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Conflict of interest statement

Competing interests: The authors declare that they have no competing interests.

No competing interests were disclosed.

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Figure 1.. Number of articles published per year on PubMed since 1952 to 2015 (July).
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