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Comment
. 2016 Feb 25;164(5):827-8.
doi: 10.1016/j.cell.2016.02.015.

Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi

Affiliations
Comment

Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi

Jeongmin Song et al. Cell. .
No abstract available

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Figures

Figure 1
Figure 1. TLR11 −/− mice do not support S. Typhi replication
(A–G) Groups of sex- and age (6 to 10 weeks)-matched control and TLR11−/− mice were infected with the indicated S. Typhi strains. Infection routes and doses are indicated in the figure panels. Shown are c. f. u. 24 days after infection obtained from spleens of animals infected with S. Typhi Ty2 (A–C), ISP2825 (D and E), A8/14353363984-6 (F) and 3290A481 (G). (H) Groups (n = 5) of male and female mice aged 9 to 14 weeks were inoculated via oral gavage with approximately 1×1010 CFU of S. Typhi Ty2 in a volume of 0.2 ml. Fresh fecal pellets were collected at indicated time points. (I and J) Mice infected intravenously infectd with the indicated dozes of S. Typhi Ty2 and the c. f. u. in spleens (I) and livers (J) enumerated 8 days after infection. See supplemental experimental procedures for information on each laboratory’s experimental contributions.

Comment in

Comment on

  • A mouse model of Salmonella typhi infection.
    Mathur R, Oh H, Zhang D, Park SG, Seo J, Koblansky A, Hayden MS, Ghosh S. Mathur R, et al. Cell. 2012 Oct 26;151(3):590-602. doi: 10.1016/j.cell.2012.08.042. Cell. 2012. PMID: 23101627 Free PMC article.

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