Optimizing dissolution dynamic nuclear polarization
- PMID: 26920826
- DOI: 10.1016/j.jmr.2015.12.007
Optimizing dissolution dynamic nuclear polarization
Abstract
This article is a short review of some of our recent developments in dissolution dynamic nuclear polarization (d-DNP). We present the basic principles of d-DNP, and motivate our choice to step away from conventional approaches. We then introduce a modified d-DNP recipe that can be summed up as follows. (i) Using broad line polarizing agents to efficiently polarize 1H spins. (ii) Increasing the magnetic field to 6.7 T and above. (iii) Applying microwave frequency modulation. (iv) Applying (1)H-(13)C cross polarization. (v) Transferring hyperpolarized solution through a magnetic tunnel.
Keywords: Cross polarization; Dissolution dynamic nuclear polarization; Hyperpolarization.
Copyright © 2015 Elsevier Inc. All rights reserved.
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