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Review
. 2016 Mar:264:13-21.
doi: 10.1016/j.jmr.2015.12.007.

Optimizing dissolution dynamic nuclear polarization

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Review

Optimizing dissolution dynamic nuclear polarization

Aurélien Bornet et al. J Magn Reson. 2016 Mar.

Abstract

This article is a short review of some of our recent developments in dissolution dynamic nuclear polarization (d-DNP). We present the basic principles of d-DNP, and motivate our choice to step away from conventional approaches. We then introduce a modified d-DNP recipe that can be summed up as follows. (i) Using broad line polarizing agents to efficiently polarize 1H spins. (ii) Increasing the magnetic field to 6.7 T and above. (iii) Applying microwave frequency modulation. (iv) Applying (1)H-(13)C cross polarization. (v) Transferring hyperpolarized solution through a magnetic tunnel.

Keywords: Cross polarization; Dissolution dynamic nuclear polarization; Hyperpolarization.

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