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Review
. 2016 May:84:23-36.
doi: 10.1016/j.micron.2016.02.005. Epub 2016 Feb 11.

Overview of chemical imaging methods to address biological questions

Marcel Menezes Lyra da Cunha  1 , Sylvain Trepout  2 , Cédric Messaoudi  2 , Ting-Di Wu  2 , Richard Ortega  3 , Jean-Luc Guerquin-Kern  2 , Sergio Marco  4
Affiliations
Free article
Review

Overview of chemical imaging methods to address biological questions

Marcel Menezes Lyra da Cunha et al. Micron. 2016 May.
Free article

Abstract

Chemical imaging offers extensive possibilities for better understanding of biological systems by allowing the identification of chemical components at the tissue, cellular, and subcellular levels. In this review, we introduce modern methods for chemical imaging that can be applied to biological samples. This work is mainly addressed to the biological sciences community and includes the bases of different technologies, some examples of its application, as well as an introduction to approaches on combining multimodal data.

Keywords: EELS; EFTEM; NanoSIMS; PIXE; STEM; Synchrotron radiation micro-analysis.

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