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Review
. 1989 Oct;5(10):331-6.
doi: 10.1016/0168-9525(89)90138-8.

Genomic imprinting and genetic disorders in man

W Reik
Review

Genomic imprinting and genetic disorders in man

W Reik. Trends Genet. 1989 Oct.

Abstract

In a considerable number of genetic disorders in the human, the phenotypic expression of the disease can depend on maternal or paternal inheritance of the mutation. It is suggested that genomic imprinting, an epigenetic process that marks maternal and paternal chromosomes in mammals, is involved in such parental effects.

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