Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Apr:2013:1206-1209.
doi: 10.1109/ISBI.2013.6556697.

A PEDIATRIC AIRWAY ATLAS AND ITS APPLICATION IN SUBGLOTTIC STENOSIS

Yi Hong  1 , Marc Niethammer  2 , Johan Andruejol  3 , Julia S Kimbell  1 , Elizabeth Pitkin  1 , Richard Superfine  1 , Stephanie Davis  4 , Carlton J Zdanski  1 , Brad Davis  3
Affiliations

A PEDIATRIC AIRWAY ATLAS AND ITS APPLICATION IN SUBGLOTTIC STENOSIS

Yi Hong et al. Proc IEEE Int Symp Biomed Imaging. 2013 Apr.

Abstract

Young children with upper airway problems are at risk for hypoxia, respiratory insufficiency and long term morbidity. Computational models and quantitative analysis would reveal airway growth patterns and benefit clinical care. To capture expected growth patterns we propose a method to build a pediatric airway atlas as a function of age. The atlas is based on a simplified airway model in combination with kernel regression. We show experimental results on children with subglottic stenosis to demonstrate that our method is able to track and measure the stenosis in pediatric airways.

Keywords: Pediatric airway atlas; simplified airway model; subglottic stenosis; weighted percentiles.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Our automatic airway segmentation (left) and an airway geometry with five landmarks (right).
Fig. 2
Fig. 2
The iso-surfaces (left), the centerline and cross sections (middle), and the 1D curve (right) for a control subject.
Fig. 3
Fig. 3
The unregistered (left) and registered (right) curves.
Fig. 4
Fig. 4
The first principle component of PCA on curves between TVC and trachea carina. Colors represent age, which is clearly a predictor of airway size.
Fig. 5
Fig. 5
Pediatric airway atlas at 30 (left) and 140 (right) months represented by weighted percentiles, for which x-axis is the depth along the centerline and y-axis is the crosssectional area (mm2).
Fig. 6
Fig. 6
Comparison of SGS03 between pre and post surgery.
See this image and copyright information in PMC

References

    1. Daniel SJ. The upper airway: Congential malformations. Pediatric Respiratory Reviews. 2006 Jun;7S:S260–S263. - PubMed
    1. Arens R, mcDonough JM, Corbin AM, Rubin NK, Carroll ME, Pack AI, Liu J, Udupa JK. Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome. American Journal of Respiratory and Critical Care Medicine. 2003 Oct;167:65–70. - PubMed
    1. Shiota S, Ryan CM, Chiu KL, Ruttanaumpawan P, Haight J, Arzt M, Floras JS, Chan C, Bradley TD. Alterations in upper airway crosssectional area in response to lower body positive pressure in healthy subjects. Thorax. 2007 Apr;62:868–872. - PMC - PubMed
    1. Wand MP, Jones MC. Kernel Smoothing. Chapman and Hall/CRC Press; 1994.
    1. Myer CM, O’Connor DM, Cotton RT. Proposed grading system for subglottic stenosis based on endotracheal tube sizes. Ann Otol Rhinol Laryngol. 1994 Apr;103:319–323. - PubMed

LinkOut - more resources