[Rupture of neoplastic intracranial aneurysm caused by metastatic uterine choriocarcinoma]

Abstract

Authors report a case of 18 years old woman with intracranial neoplastic aneurysm. Its rupture occurred one month after delivery, and the diagnosis of metastatic aneurysm from choriocarcinoma was made by pathologist. The craniotomy has allowed to remove the hematoma and the aneurysm with good immediate follow-up. In spite of X-ray-therapy and chemotherapy, the patient died one year after the outset from choriocarcinoma dissemination, in a comatose state. The review of the literature shows that this form of aneurysm is very exceptional. It is resulting from the invasion of the arterial wall by metastatic cells, by a neighbouring metastatic tumor or by another type of brain-tumor. In some cases, the aneurysmal rupture was the first symptom, before any gynecologic manifestation of the choriocarcinoma. The prognosis has been bad in such cases in spite of a commonly good response after chemotherapy.