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. 2016 Jun;37(5):868-77.
doi: 10.1007/s00246-016-1361-3. Epub 2016 Mar 1.

Hybrid Palliation for Ductal-Dependent Systemic Circulation

William N Evans  1   2 , Alvaro Galindo  3   4 , Abraham Rothman  3   4 , Michael L Ciccolo  3   5 , Sergio A Carrillo  3   5 , Ruben J Acherman  3   4 , Gary A Mayman  3   4 , Kathleen A Cass  3   4 , Katrinka T Kip  3   4 , Carlos F Luna  3   4 , Joseph M Ludwick  3   4 , Robert C Rollins  3   4 , William J Castillo  3   4 , John A Alexander  3   4 , Humberto Restrepo  3   4
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Hybrid Palliation for Ductal-Dependent Systemic Circulation

William N Evans et al. Pediatr Cardiol. 2016 Jun.

Abstract

We reviewed our hybrid palliation experience for 91 neonates, with ductal-dependent systemic circulation, born between August 2007 and October 2015. For analysis, we stratified the 91 patients by a risk factor (RF) score and divided them into three groups: (1) high-risk two-functional ventricles (2V) median RF score of 3 (N = 20); (2) low-risk one-functional ventricle (1V) RF score 0-1 (N = 32); and (3) high-risk 1V RF score ≥2 (N = 39). Midterm survival (median 4 years) by group was: (1) 95 %, (2) 91 %, and (3) 15 %, (p = 0.001). In conclusion, hybrid palliation was associated with excellent midterm results for high-risk 2V and low-risk 1V patients with ductal-dependent systemic circulation. In contrast, high-risk 1V patients had significantly worse outcomes.

Keywords: Ductal-dependent systemic circulation; Hybrid procedure; Hypoplastic aortic arch; Hypoplastic left heart syndrome.

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