Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Mar 15;62 Suppl 1(Suppl 1):S50-5.
doi: 10.1093/cid/civ789.

Prevalence of Salmonella Excretion in Stool: A Community Survey in 2 Sites, Guinea-Bissau and Senegal

Justin Im  1 , Chelsea Nichols  1 , Morten Bjerregaard-Andersen  2 , Amy Gassama Sow  3 , Sandra Løfberg  2 , Adama Tall  4 , Gi Deok Pak  1 , Peter Aaby  2 , Stephen Baker  5 , John D Clemens  6 , Ligia Maria Cruz Espinoza  1 , Frank Konings  1 , Jürgen May  7 , Mario Monteiro  2 , Aissatou Niang  4 , Ursula Panzner  1 , Se Eun Park  1 , Heidi Schütt-Gerowitt  8 , Thomas F Wierzba  1 , Florian Marks  1 , Vera von Kalckreuth  1
Affiliations

Prevalence of Salmonella Excretion in Stool: A Community Survey in 2 Sites, Guinea-Bissau and Senegal

Justin Im et al. Clin Infect Dis. .

Abstract

Background: Chronic and convalescent carriers play an important role in the transmission and endemicity of many communicable diseases. A high incidence of Salmonella enterica serovar Typhi and invasive nontyphoidal Salmonella (NTS) infection has been reported in parts of sub-Saharan Africa, yet the prevalence of Salmonella excretion in the general population is unknown.

Methods: Stool specimens were collected from a random sample of households in 2 populations in West Africa: Bissau, Guinea-Bissau, and Dakar, Senegal. Stool was cultured to detect presence of Salmonella, and antimicrobial susceptibility testing was performed on the isolated organisms.

Results: Stool was cultured from 1077 and 1359 individuals from Guinea-Bissau and Senegal, respectively. Salmonella Typhi was not isolated from stool samples at either site. Prevalence of NTS in stool samples was 24.1 (95% confidence interval [CI], 16.5-35.1; n = 26/1077) per 1000 population in Guinea-Bissau and 10.3 (95% CI, 6.1-17.2; n = 14/1359) per 1000 population in Senegal.

Conclusions: Evidence of NTS excretion in stool in both study populations indicates a possible NTS transmission route in these settings.

Keywords: NTS; Salmonella; carrier; stool culture; typhoid.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Cruickshank JG, Humphrey TJ. The carrier food-handler and non-typhoid salmonellosis. Epidemiol Infect 1987; 98:223–30. - PMC - PubMed
    1. Levine MM, Robins-Browne RM. Factors that explain excretion of enteric pathogens by persons without diarrhea. Clin Infect Dis 2012; 55(suppl 4):S303–11. - PMC - PubMed
    1. Buchwald DS, Blaser MJ. A review of human salmonellosis: II. Duration of excretion following infection with non-typhi Salmonella. Rev Infect Dis 1984; 6:345–56. - PubMed
    1. Sharp JC. Convalescent excretion of salmonellae and shigellae. Health Bull 1970; 28:19–22. - PubMed
    1. Abboud ES, Wahba AH. Enteric fever carriage with special reference to the incidence of paratyphoid C in Egypt. J Egypt Public Health Assoc 1966; 41:319–27. - PubMed

Publication types

MeSH terms

Substances