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. 2016 Mar 15;62 Suppl 1(Suppl 1):S50-5.
doi: 10.1093/cid/civ789.

Prevalence of Salmonella Excretion in Stool: A Community Survey in 2 Sites, Guinea-Bissau and Senegal

Justin Im  1 , Chelsea Nichols  1 , Morten Bjerregaard-Andersen  2 , Amy Gassama Sow  3 , Sandra Løfberg  2 , Adama Tall  4 , Gi Deok Pak  1 , Peter Aaby  2 , Stephen Baker  5 , John D Clemens  6 , Ligia Maria Cruz Espinoza  1 , Frank Konings  1 , Jürgen May  7 , Mario Monteiro  2 , Aissatou Niang  4 , Ursula Panzner  1 , Se Eun Park  1 , Heidi Schütt-Gerowitt  8 , Thomas F Wierzba  1 , Florian Marks  1 , Vera von Kalckreuth  1
Affiliations

Prevalence of Salmonella Excretion in Stool: A Community Survey in 2 Sites, Guinea-Bissau and Senegal

Justin Im et al. Clin Infect Dis. .

Abstract

Background: Chronic and convalescent carriers play an important role in the transmission and endemicity of many communicable diseases. A high incidence of Salmonella enterica serovar Typhi and invasive nontyphoidal Salmonella (NTS) infection has been reported in parts of sub-Saharan Africa, yet the prevalence of Salmonella excretion in the general population is unknown.

Methods: Stool specimens were collected from a random sample of households in 2 populations in West Africa: Bissau, Guinea-Bissau, and Dakar, Senegal. Stool was cultured to detect presence of Salmonella, and antimicrobial susceptibility testing was performed on the isolated organisms.

Results: Stool was cultured from 1077 and 1359 individuals from Guinea-Bissau and Senegal, respectively. Salmonella Typhi was not isolated from stool samples at either site. Prevalence of NTS in stool samples was 24.1 (95% confidence interval [CI], 16.5-35.1; n = 26/1077) per 1000 population in Guinea-Bissau and 10.3 (95% CI, 6.1-17.2; n = 14/1359) per 1000 population in Senegal.

Conclusions: Evidence of NTS excretion in stool in both study populations indicates a possible NTS transmission route in these settings.

Keywords: NTS; Salmonella; carrier; stool culture; typhoid.

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