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Case Reports
. 2016 Jan 30;9(1):83-8.
doi: 10.1159/000443722. eCollection 2016 Jan-Apr.

Langerhans Cell Histiocytosis of the Rib in an Adult: A Case Report

Sung Hyun Kim  1 , Moon Young Choi  1
Affiliations
Case Reports

Langerhans Cell Histiocytosis of the Rib in an Adult: A Case Report

Sung Hyun Kim et al. Case Rep Oncol. .

Abstract

Single-site, single-system Langerhans cell histiocytosis (LCH) of the rib is one of the rarest causes of bone tumor in adults. Herein, we report a case of a healthy 35-year-old male who presented with upper back pain that was attributed to a solitary osteolytic lesion at the posterolateral aspect of his sixth rib. For diagnostic confirmation and treatment, partial resection of the sixth rib was performed and pathologic finding was consistent with LCH. At the final follow-up after 2 years, no local recurrence or metastasis was observed.

Keywords: Adult; Langerhans cell histiocytosis; Rib.

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Figures

Fig. 1
Fig. 1
Simple X-ray (a) and chest CT (b) showed a focal osteolytic lesion in the posterior arc of the left sixth rib. PET (c, d) revealed a solitary hypermetabolic lesion (SUVmax 7.1) at that site.
Fig. 2
Fig. 2
Histologic findings showed proliferation of histiocytes and eosinophil infiltration. Immunohistochemical stains were positive for S100 and CD1a, and negative for CD68.
See this image and copyright information in PMC

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