Challenges in RCC Imaging: Renal Insufficiency, Post-Operative Surveillance, and the Role of Radiomics

. 2015 Nov;13(4):84-90.

Challenges in RCC Imaging: Renal Insufficiency, Post-Operative Surveillance, and the Role of Radiomics

Nicholas J Farber¹, Yan Wu², Lily Zou³, Puneet Belani³, Eric A Singer⁴

Affiliations

¹ Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, Room 4563 New Brunswick, NJ 08903, USA.
² Center for Biomedical Imaging & Informatics, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 195 Little Albany Street, New Brunswick, NJ 08903, USA; Rutgers Robert Wood Johnson Medical School, Department of Radiology, MEB #404 P.O. Box 19, New Brunswick, NJ 08903, USA.
³ Rutgers Robert Wood Johnson Medical School, Department of Radiology, MEB #404 P.O. Box 19, New Brunswick, NJ 08903, USA.
⁴ Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, Room 4563 New Brunswick, NJ 08903, USA; Center for Biomedical Imaging & Informatics, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 195 Little Albany Street, New Brunswick, NJ 08903, USA.

PMID: 26937265
PMCID: PMC4770557

Challenges in RCC Imaging: Renal Insufficiency, Post-Operative Surveillance, and the Role of Radiomics

Nicholas J Farber et al. Kidney Cancer J. 2015 Nov.

. 2015 Nov;13(4):84-90.

Authors

Nicholas J Farber¹, Yan Wu², Lily Zou³, Puneet Belani³, Eric A Singer⁴

Affiliations

¹ Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, Room 4563 New Brunswick, NJ 08903, USA.
² Center for Biomedical Imaging & Informatics, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 195 Little Albany Street, New Brunswick, NJ 08903, USA; Rutgers Robert Wood Johnson Medical School, Department of Radiology, MEB #404 P.O. Box 19, New Brunswick, NJ 08903, USA.
³ Rutgers Robert Wood Johnson Medical School, Department of Radiology, MEB #404 P.O. Box 19, New Brunswick, NJ 08903, USA.
⁴ Rutgers Robert Wood Johnson Medical School, Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, Room 4563 New Brunswick, NJ 08903, USA; Center for Biomedical Imaging & Informatics, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, 195 Little Albany Street, New Brunswick, NJ 08903, USA.

PMID: 26937265
PMCID: PMC4770557

No abstract available

Keywords: Renal cell carcinoma imaging; diffusion MRI; kidney cancer surveillance; molecular imaging; perfusion MRI; radiation exposure.

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Figures

**Figure 1. Perfusion MRI**
Coronal T1-weighted MRI (left) and Dynamic contrast-enhanced (DCE) MRI (right) of a right renal mass. 3D perfusion parametric map was obtained showing the microcirculation of the mass. Red color indicates a high level of perfusion. Pathology revealed clear cell RCC, Fuhrman grade 4. Reproduced from Wu et al. with permission.

**Figure 2. Diffusion Weighted MRI**
Axial DWI (left) and ADC (right) images of the same right renal mass with a b value of 800 s/mm². On DWI, the high-grade clear cell RCC appears hyperintense, showing restricted diffusion, while the ADC map shows hypointensity, confirming this finding. Reproduced from Wu et al. with permission.

See this image and copyright information in PMC

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References

1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA: a cancer journal for clinicians. 2015 Jan-Feb;65(1):5–29. - PubMed
1. Chow WH, Devesa SS, Warren JL, Fraumeni JF., Jr. Rising incidence of renal cell cancer in the United States. Jama. 1999 May 5;281(17):1628–1631. - PubMed
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[1] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA: a cancer journal for clinicians. 2015 Jan-Feb;65(1):5–29. - PubMed

[2] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA: a cancer journal for clinicians. 2015 Jan-Feb;65(1):5–29. - PubMed

[3] Chow WH, Devesa SS, Warren JL, Fraumeni JF., Jr. Rising incidence of renal cell cancer in the United States. Jama. 1999 May 5;281(17):1628–1631. - PubMed

[4] Chow WH, Devesa SS, Warren JL, Fraumeni JF., Jr. Rising incidence of renal cell cancer in the United States. Jama. 1999 May 5;281(17):1628–1631. - PubMed

[5] Media ACoDaC. ACR Manual on Contrast Media. 10.1 ed2015:33-44

[6] Media ACoDaC. ACR Manual on Contrast Media. 10.1 ed2015:33-44

[7] Elicker BM, Cypel YS, Weinreb JC. IV contrast administration for CT: a survey of practices for the screening and prevention of contrast nephropathy. AJR. American journal of roentgenology. 2006 Jun;186(6):1651–1658. - PubMed

[8] Elicker BM, Cypel YS, Weinreb JC. IV contrast administration for CT: a survey of practices for the screening and prevention of contrast nephropathy. AJR. American journal of roentgenology. 2006 Jun;186(6):1651–1658. - PubMed

[9] Weisbord SD, Palevsky PM. Prevention of contrast-induced nephropathy with volume expansion. Clinical journal of the American Society of Nephrology : CJASN. 2008 Jan;3(1):273–280. - PubMed

[10] Weisbord SD, Palevsky PM. Prevention of contrast-induced nephropathy with volume expansion. Clinical journal of the American Society of Nephrology : CJASN. 2008 Jan;3(1):273–280. - PubMed

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Challenges in RCC Imaging: Renal Insufficiency, Post-Operative Surveillance, and the Role of Radiomics

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Challenges in RCC Imaging: Renal Insufficiency, Post-Operative Surveillance, and the Role of Radiomics

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