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Randomized Controlled Trial
. 2016 Feb;95(8):e2835.
doi: 10.1097/MD.0000000000002835.

Enhanced Recovery Program Versus Traditional Care in Laparoscopic Hepatectomy

Xiao Liang  1 , Hanning Ying, Hongwei Wang, Hongxia Xu, Hong Yu, Liuxin Cai, Yifan Wang, Yifan Tong, Lin Ji, Raojun Luo, Xiu-Jun Cai
Affiliations
Randomized Controlled Trial

Enhanced Recovery Program Versus Traditional Care in Laparoscopic Hepatectomy

Xiao Liang et al. Medicine (Baltimore). 2016 Feb.

Abstract

Enhanced recovery after surgery (ERAS) has shown effectiveness in terms of reducing the hospital stay and cost associated with open liver resection. However, the benefit of ERAS in patients undergoing laparoscopic liver resection is still unclear, and clinical studies on this topic are limited.The ERAS program for laparoscopic liver resection was used in a group of 80 patients (ERAS group). The results were compared with those in a control group of 107 patients. All patients underwent laparoscopic liver resection. The primary endpoints were the postoperative hospital stay, defined as the number of days from surgery to discharge, and the hospitalization expense. The secondary endpoints were resumption of oral intake, readmissions, and complications.The median postoperative hospital stay was 6.2 ± 2.6 days in the ERAS group, which was significantly shorter than that in the control group (9.9 ± 5.9 d; P < 0.001). The hospitalization cost was $6871 ± 2571 in the ERAS group and $7948 ± 3630 in the control group (P = 0.020). The morbidity rate was 22.5% (18 of 80 patients) in the ERAS group and 43.9% (47 of 107 patients) in the control group (P = 0.002). There were no significant differences the in rate of readmission between the 2 groups.Enhanced recovery after surgery for laparoscopic liver resection is safe and effective. Patients in the ERPS group had a shorter hospital stay, fewer complications, and lower hospital costs.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Pain score in the control group (red line) was higher than that in the early recovery after surgery (ERAS) group (blue line). The pain score was significantly different between the 2 groups on days 1, 3, and 5 (all P < 0.001). The P values were measured by the t test.
FIGURE 2
FIGURE 2
Functional recovery after surgery was achieved at 5.0 ± 2.3 days in the early recovery after surgery (ERAS) group and 8.5 ± 4.4 days in the control group (∗P < 0.001). The postoperative hospital stay was 6.2 ± 2.6 days in the ERAS group and 9.9 ± 5.9 days in the control group (∗∗P < 0.001). The P values were measured by the t test.
See this image and copyright information in PMC

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