Identification of synaptic acetylcholine receptor sites in retina with peroxidase-labeled alpha-bungarotoxin
- PMID: 269390
- PMCID: PMC431525
- DOI: 10.1073/pnas.74.8.3268
Identification of synaptic acetylcholine receptor sites in retina with peroxidase-labeled alpha-bungarotoxin
Abstract
An alpha-bungarotoxin-horseradish peroxidase conjugate, which binds specificity to nicotinic acetylcholine receptors, was synthesized. This conjugate was bound by 5-7% of the synapses in the inner plexiform layer of the chicken retina. Bipolar ribbon synapses as well as amacrine synapses bound the conjugate.
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