FOXO3a & haematopoietic stem cells: Goodbye PI3K, hello SIRT1?
- PMID: 26940015
- PMCID: PMC4889269
- DOI: 10.1080/15384101.2016.1151721
FOXO3a & haematopoietic stem cells: Goodbye PI3K, hello SIRT1?
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Evidence for AKT-independent regulation of FOXO1 and FOXO3 in haematopoietic stem and progenitor cells.Cell Cycle. 2016;15(6):861-7. doi: 10.1080/15384101.2015.1123355. Cell Cycle. 2016. PMID: 26929388 Free PMC article.
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References
-
- Lee JY, et al.. Cell Stem Cell 2010; 7(5):593-605; PMID:21040901; http://dx.doi.org/10.1016/j.stem.2010.09.015 - DOI - PMC - PubMed
-
- Chen C, et al.. J Exp Med 2008; 205(10):2397-408; PMID:18809716; http://dx.doi.org/10.1084/jem.20081297 - DOI - PMC - PubMed
-
- Li X, et al.. J Biol Chem 2015; 290(5):2715-27; PMID:25505262; http://dx.doi.org/10.1074/jbc.M114.619536 - DOI - PMC - PubMed
-
- Liang R, et al.. Cell Cycle 2016; 15(6):861-7; PMID:26929388; http://dx.doi.org/10.1080/15384101.2015.112335516272144
-
- Matsuzaki H, et al.. J Biochem 2005; 138(4):485-91; PMID:16272144; http://dx.doi.org/10.1093/jb/mvi146 - DOI - PubMed
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