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Randomized Controlled Trial
. 2016 Mar 3;6(3):e010203.
doi: 10.1136/bmjopen-2015-010203.

Randomised controlled trial of referral to a telephone-based weight management and healthy lifestyle programme for patients with knee osteoarthritis who are overweight or obese: a study protocol

Kate M O'Brien  1 , John Wiggers  1 , Amanda Williams  1 , Elizabeth Campbell  1 , Luke Wolfenden  1 , Serene Yoong  1 , Emma K Robson  2 , James McAuley  3 , Robin Haskins  4 , Steven J Kamper  5 , Christopher Williams  6
Affiliations
Randomized Controlled Trial

Randomised controlled trial of referral to a telephone-based weight management and healthy lifestyle programme for patients with knee osteoarthritis who are overweight or obese: a study protocol

Kate M O'Brien et al. BMJ Open. .

Abstract

Introduction: Knee osteoarthritis (OA) is one of the most common chronic diseases worldwide and is associated with significant pain and disability. Clinical practice guidelines consistently recommend weight management as a core aspect of care for overweight and obese patients with knee OA; however, provision of such care is suboptimal. Telephone-based interventions offer a novel approach to delivery of weight management care in these patients. The aim of the proposed study is to assess the effectiveness of referral to a telephone-based weight management and healthy lifestyle programme, previously shown to be effective in changing weight, in improving knee pain intensity in overweight or obese patients with knee OA, compared to usual care.

Methods and analysis: A parallel, randomised controlled trial will be undertaken. Patients with OA of the knee who are waiting for an outpatient orthopaedic consultation at a tertiary referral public hospital within New South Wales, Australia, will be allocated to either an intervention or a control group (1:1 ratio). After baseline data collection, patients in the intervention group will receive a 6-month telephone-based intervention, and patients in the control group will continue with usual care. Surveys will be conducted at baseline, 6 and 26 weeks post-randomisation. The study requires 60 participants per group to detect a two-point difference in pain intensity (primary outcome) 26 weeks after baseline.

Ethics and dissemination: The study is approved by the Hunter New England Health Human Research Ethics Committee (13/12/11/5.18) and the University of Newcastle Human Research Ethics Committee (H-2015-0043). The results will be disseminated in peer-reviewed journals and at scientific conferences.

Trial registration number: ACTRN12615000490572, Pre-results.

Keywords: PAIN MANAGEMENT.

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Figure 1
Flow diagram describing progress of participants through the study.
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References

    1. Murray CJ, Vos T, Lozano R et al. . Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2197–223. 10.1016/S0140-6736(12)61689-4 - DOI - PubMed
    1. Vos T, Flaxman AD, Naghavi M et al. . Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2163–96. 10.1016/S0140-6736(12)61729-2 - DOI - PMC - PubMed
    1. Felson DT, Lawrence RC, Dieppe PA et al. . Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 2000;133:635–46. 10.7326/0003-4819-133-8-200010170-00016 - DOI - PubMed
    1. GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015;385:117–71. 10.1016/S0140-6736(14)61682-2 - DOI - PMC - PubMed
    1. Access Economics (Firm) & Diabetes Australia. The economic costs of obesity. Canberra, Australia: Diabetes Australia; Access Economics, 2006.

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