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Review
. 2016 Mar;9(1):11-28.
doi: 10.1016/j.path.2015.09.007.

B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation

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Review

B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation

Charles M Harmon et al. Surg Pathol Clin. 2016 Mar.

Abstract

B-cell non-Hodgkin lymphomas with plasmacytic differentiation are a diverse group of entities with extremely variable morphologic features. Diagnostic challenges can arise in differentiating lymphoplasmacytic lymphoma from marginal zone lymphoma and other low-grade B-cell lymphomas. In addition, plasmablastic lymphomas can be difficult to distinguish from diffuse large B-cell lymphoma or other high-grade lymphomas. Judicious use of immunohistochemical studies and molecular testing can assist in appropriate classification.

Keywords: Lymphoma; Lymphoplasmacytic; MALT; Nodal marginal zone; Plasmablastic; Plasmacytic; Splenic.

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