Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review
- PMID: 26941815
- PMCID: PMC4755098
- DOI: 10.4103/1735-1995.172835
Benzofuran as a promising scaffold for the synthesis of antimicrobial and antibreast cancer agents: A review
Abstract
Benzofuran as an important heterocyclic compound is extensively found in natural products as well as synthetic materials. Since benzofuran drivatives display a diverse array of pharmacological activities, an interest in developing new biologically active agents from benzofuran is still under consideration. This review highlights recent findings on biological activities of benzofuran derivatives as antimicrobial and antibreast cancer agents and lays emphasis on the importance of benzofurans as a major source for drug design and development.
Keywords: Benzofuran; anti breast cancer; antibacterial.
References
-
- Dawood KM. Benzofuran derivatives: A patent review. Expert Opin Ther Pat. 2013;23:1133–56. - PubMed
-
- Habtemariam S. Antiinflammatory activity of the antirheumatic herbal drug, gravel root (Eupatorium purpureum): Further biological activities and constituents. Phytother Res. 2001;15:687–90. - PubMed
-
- Pauletti PM, Araújo AR, Young MC, Giesbrecht AM, Bolzani VD. nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity. Phytochemistry. 2000;55:597–601. - PubMed
-
- Masubuchi M, Kawasaki K, Ebiike H, Ikeda Y, Tsujii S, Sogabe S, et al. Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1. Bioorg Med Chem Lett. 2001;11:1833–7. - PubMed
-
- Wrobel JE, Dietrich AJ, Antane MM. Benzothiophenes, Benzofurans, and Indoles Useful in the Treatment of Insulin Resistance and Hyperglycemia. US Patent 6,251,936. 2001:1–57.
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