Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Mar 5:16:23.
doi: 10.1186/s12886-016-0199-z.

Management of intraocular pressure elevation during hemodialysis of neovascular glaucoma: a case report

Affiliations
Case Reports

Management of intraocular pressure elevation during hemodialysis of neovascular glaucoma: a case report

P Frezzotti et al. BMC Ophthalmol. .

Abstract

Background: It is generally accepted that dialysis may lower plasma osmolality at a faster rate than changes in ocular osmolality. This osmotic difference causes water to migrate from the plasma into the aqueous humor, increasing intraocular pressure. Certain authors have described IOP increase in patients with narrow angles.

Case presentation: Here we report a neovascular glaucoma patient who experienced a substantial increase in IOP associated with severe eye pain and blurred vision during sessions of dialysis. The patient had been refractory to several antiglaucoma drugs and improved after intravenous administration of 20% hyperosmotic glucose solution with dialysis and pan-retinal photocoagulation.

Conclusion: It is the first report in which intravenous glucose administration and reduction of neovascularization by argon laser pan-retinal photocoagulation successfully managed IOP increase during dialysis in neovascular glaucoma. Further clinical studies are required to confirm our results.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Biomicroscopic (a) and OCT (b) images of anterior chamber showing angle closure due to neovascularization of the angle
Fig. 2
Fig. 2
Appearance of ONH in right eye
Fig. 3
Fig. 3
Differences between IOP before and after i.v. glucose and panretinal photocoagulation treatments

References

    1. Evans RD, Rosner M. Ocular abnormalities associated with advanced kidney disease and hemodialysis. Semin Dial. 2005;18:252–7. doi: 10.1111/j.1525-139X.2005.18322.x. - DOI - PubMed
    1. Burn RA. Intraocular pressure during hemodialysis. Br J Ophthalmol. 1973;57:511–3. doi: 10.1136/bjo.57.7.511. - DOI - PMC - PubMed
    1. Leiba H, Oliver M, Shimshomi M, Bar-Khayim Y. Intraocular pressure fluctuations during regular hemodialysis and ultrafiltration. Acta Ophthalmol. 1990;68:320–2. doi: 10.1111/j.1755-3768.1990.tb01930.x. - DOI - PubMed
    1. Jung SK, Lee SK, Kim JH. Intraocular pressure change by hemodialysis. J Korean Ophthalmol Soc. 1995;36:2195–201.
    1. Choong YF, Menage MJ. Symptomatic acute raised IOP following hemodialysis in a patient with end stage renal failure. Br J Ophthalmol. 1998;82:1342–50. - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources