[Pregnancy-associated alpha2-glycoprotein (alpha2-PAG)--past, present and future]
- PMID: 2694688
[Pregnancy-associated alpha2-glycoprotein (alpha2-PAG)--past, present and future]
Abstract
The pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG), first described 30 years ago, is a high-molecular neuramino-glycoprotein. Its serum concentration is normally low, but substantially increases during pregnancy and in some malignant tumour diseases. A review is given of occurrence and quantification of alpha 2-PAG under physiological and pathophysiological conditions, site of synthesis and localization, purification and physico-chemical properties, biological role and possible clinical use.
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