A Novel Mechanism of Immune Memory Unveiled at the Invertebrate-Parasite Interface
- PMID: 26953517
- DOI: 10.1016/j.pt.2016.02.005
A Novel Mechanism of Immune Memory Unveiled at the Invertebrate-Parasite Interface
Abstract
Pinaud et al. recently provided the first global investigation of the molecular processes underlying innate immune memory in an invertebrate species. They showed that the memory response of the snail Biomphalaria glabrata to Schistosoma mansoni infection is associated with a shift from cellular to humoral mechanisms.
Keywords: Biomphalaria glabrata; Schistosoma mansoni; host–parasite interaction; immune priming; trained immunity.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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A Shift from Cellular to Humoral Responses Contributes to Innate Immune Memory in the Vector Snail Biomphalaria glabrata.PLoS Pathog. 2016 Jan 6;12(1):e1005361. doi: 10.1371/journal.ppat.1005361. eCollection 2016 Jan. PLoS Pathog. 2016. PMID: 26735307 Free PMC article.
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