Developmental Patterning: Putting the Squeeze on Mis-specified Cells
- PMID: 26954441
- DOI: 10.1016/j.cub.2016.01.010
Developmental Patterning: Putting the Squeeze on Mis-specified Cells
Abstract
Widely implicated in human disease, abnormal cellular cysts reflect dramatic defects in the maintenance of epithelial integrity. A new study reports that epithelial cysts may arise as a surprisingly general consequence of clonal defects in the specification of cell identity.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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Interface Contractility between Differently Fated Cells Drives Cell Elimination and Cyst Formation.Curr Biol. 2016 Mar 7;26(5):563-74. doi: 10.1016/j.cub.2015.12.063. Epub 2016 Feb 4. Curr Biol. 2016. PMID: 26853359 Free PMC article.
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