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Review
. 2016;31(1-2):91-8.
doi: 10.3109/08820538.2015.1114862.

Autologous Limbal Stem Cell Transplantation: The Progression of Diagnosis and Treatment

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Review

Autologous Limbal Stem Cell Transplantation: The Progression of Diagnosis and Treatment

Haumith Khan-Farooqi et al. Semin Ophthalmol. 2016.

Abstract

Though the corneoscleral limbus has been studied for more than 150 years, our ability to successfully treat those with limbal stem cell deficiency (LSCD) is still a work in progress. Today, the only definitive cure for LSCD is stem cell transplantation. This review briefly discusses the evolution of our understanding of limbal stem cell function, provides an outline of the history of autologous limbal stem cell (LSC) transplantation, and discusses current techniques and future strategies for LSCD treatment.

Keywords: Cornea; epithelium; limbal stem cell deficiency; limbus; transplant.

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