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Comment
. 2016 Apr;22(4):267-269.
doi: 10.1016/j.molmed.2016.02.007. Epub 2016 Mar 7.

'Mitotherapy' for Heart Failure

Fabian Sanchis-Gomar  1 , Giuseppe Lippi  2 , Alejandro Lucia  3
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Comment

'Mitotherapy' for Heart Failure

Fabian Sanchis-Gomar et al. Trends Mol Med. 2016 Apr.

Abstract

Abnormalities in mitochondrial dynamics along with those for the molecular mediators involved are presently being viewed with increased interest in the field of cardiovascular disease. Recent research highlights OPA1, a dynamin-like GTPase mediating mitochondrial fusion, as well as the 'mitoproteases' OMA1 and YME1L, as potential therapeutic targets against heart failure.

Keywords: aging; heart; pathway.

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