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Review
. 2016 Apr;37(2):267-76.
doi: 10.1055/s-0036-1578803. Epub 2016 Mar 14.

Lung Malignancies in HIV Infection

Keith Sigel  1 , Robert Pitts  1 , Kristina Crothers  2
Affiliations
Review

Lung Malignancies in HIV Infection

Keith Sigel et al. Semin Respir Crit Care Med. 2016 Apr.

Abstract

Pulmonary malignancies are a major source of morbidity and mortality in HIV-infected persons. Non-AIDS-defining lung cancers (mostly non-small cell lung cancers) are now a leading cause of cancer death among HIV-infected persons. HIV-associated factors appear to affect the risk of lung cancer and may adversely impact cancer treatment and outcomes. HIV infection also may modify the potential harms and benefits of lung cancer screening with computed tomography. AIDS-defining lung malignancies include pulmonary Kaposi sarcoma and pulmonary lymphoma, both of which are less prevalent with widespread adoption of antiretroviral therapy.

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