Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Mar 15:20:62.
doi: 10.1186/s13054-016-1216-6.

Variable ventilation from bench to bedside

Affiliations
Review

Variable ventilation from bench to bedside

Robert Huhle et al. Crit Care. .

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Distribution of tidal volumes (VT) according to power‐law (black) or Gaussian distribution (blue)
Fig. 2
Fig. 2
Signal traces during variable volume controlled ventilation (cVV) and variable pressure support ventilation (sVV). P aw: airway pressure
Fig. 3
Fig. 3
Microstructural (top) and macrostructural (bottom) mechanisms of variable ventilation (right side) compared to non‐variable counter‐parts (left side), with distribution of perfusion (red) and distribution of ventilation (white) within the non‐dependent (upper half) and dependent (lower half) parts of the lung; arrows indicate increase (↗), decrease (↘) and unchanged (↔) ventilation/perfusion in the respective lung region. Paw: airway pressure; Pcrit: critical opening pressure. (© Illustration by Peter Ernst)
Fig. 4
Fig. 4
Advantageous (blue) and disadvantageous (gray) ranges of alveolar pressure of variable ventilation on a representative static pressure – volume curve described by the Venegas equation with parameters a, b, c and d from [18]. ∆Psupp: change in support pressure needed to gain the displayed tidal volume (VT) in variable ventilation

Comment in

References

    1. Ivanov PC, Amaral LA, Goldberger AL, et al. Multifractality in human heartbeat dynamics. Nature. 1999;399:461–465. doi: 10.1038/20924. - DOI - PubMed
    1. Frey U, Silverman M, Barabási AL, Suki B. Irregularities and power law distributions in the breathing pattern in preterm and term infants. J Appl Physiol Bethesda Md. 1998;1985(85):789–797. - PubMed
    1. Huikuri HV, Mäkikallio TH. Heart rate variability in ischemic heart disease. Auton Neurosci Basic Clin. 2001;90:95–101. doi: 10.1016/S1566-0702(01)00273-9. - DOI - PubMed
    1. Malberg H, Bauernschmitt R, Voss A, et al. Analysis of cardiovascular oscillations: a new approach to the early prediction of pre-eclampsia. Chaos. 2007;17:015113. doi: 10.1063/1.2711660. - DOI - PubMed
    1. Penzel T, Wessel N, Riedl M, et al. Cardiovascular and respiratory dynamics during normal and pathological sleep. Chaos. 2007;17:015116. doi: 10.1063/1.2711282. - DOI - PubMed

Publication types