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Randomized Controlled Trial
. 2016 Mar 16:18:68.
doi: 10.1186/s13075-016-0954-9.

Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia

Dana L Dailey  1   2 , Laura A Frey Law  3 , Carol G T Vance  3 , Barbara A Rakel  3   4 , Ericka N Merriwether  3 , Leon Darghosian  5 , Meenakshi Golchha  5 , Katharine M Geasland  3 , Rebecca Spitz  3 , Leslie J Crofford  5 , Kathleen A Sluka  3   4
Affiliations
Randomized Controlled Trial

Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia

Dana L Dailey et al. Arthritis Res Ther. .

Abstract

Background: Fibromyalgia is a condition characterized by chronic widespread muscle pain and fatigue and associated with significant impairment in perceived function and reduced physical performance. The purpose of this study was to determine the degree to which pain and fatigue are associated with perceived function and physical performance in women with fibromyalgia.

Methods: Hierarchical linear regression determined the contribution of pain and fatigue (Numeric Rating Scale (NRS) for resting, movement and combined) to perceived function (Fibromyalgia Impact Questionnaire Revised - Function Subscale, FIQR-Function), Multidimensional Assessment of Fatigue - Activities of Daily Living (MAF-ADL) and SF-36 Physical Function Subscale (SF-36-PF) and physical performance (6-Minute Walk Test, 6MWT and Five Time Sit To Stand, 5TSTS) while controlling for age, body mass index, pain catastrophizing, fear of movement, anxiety, and depression in women with fibromyalgia (N = 94).

Results: For perceived function, movement pain and movement fatigue together better predicted FIQR-function (adjusted R(2) = 0.42, p ≤ 0.001); MAF-ADL (adjusted R(2) = 0.41, p ≤ 0.001); and SF-36-PF function (adjusted R(2) = 0.34, p ≤ 0.001). For physical performance measures, movement pain and fatigue together predicted 6MWT distance (adjusted R(2) = 0.42, p ≤ 0.001) and movement fatigue alone predicted performance time on the 5TSTS (adjusted R(2) = 0.20, p ≤ 0.001).

Conclusions: Pain and fatigue are significantly associated with and explain more than one-third of the variance in perceived function and physical performance in women with fibromyalgia.

Trial registration: NIH Clinicaltrials.gov

Registration: NCT01888640 . Registered 13 June 2013.

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References

    1. Anderson RJ, McCrae CS, Staud R, Berry RB, Robinson ME. Predictors of clinical pain in fibromyalgia: examining the role of sleep. J Pain. 2012;13:350–8. doi: 10.1016/j.jpain.2011.12.009. - DOI - PMC - PubMed
    1. Arnold LM, Crofford LJ, Mease PJ, Burgess SM, Palmer SC, Abetz L, et al. Patient perspectives on the impact of fibromyalgia. Patient Educ Couns. 2008;73:114–20. doi: 10.1016/j.pec.2008.06.005. - DOI - PMC - PubMed
    1. Bohannon RW. Test-retest reliability of the five-repetition sit-to-stand test: a systematic review of the literature involving adults. J Strength Cond Res. 2011;25:3205–7. doi: 10.1519/JSC.0b013e318234e59f. - DOI - PubMed
    1. Bennett RM, Russell J, Cappelleri JC, Bushmakin AG, Zlateva G, Sadosky A. Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis. BMC Musculoskelet Disord. 2010;11:134. doi: 10.1186/1471-2474-11-134. - DOI - PMC - PubMed
    1. Schaefer KM. Health patterns of women with fibromyalgia. J Adv Nurs. 1997;26:565–71. doi: 10.1046/j.1365-2648.1997.t01-17-00999.x. - DOI - PubMed

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