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. 2015 Sep-Dec;19(3):330-4.
doi: 10.4103/0973-029X.174614.

Reactive hyperplasic lesions of the oral cavity: A survey of 295 cases at a Tertiary Health Institution in Kerala

S Vidyanath  1 , P M Shameena  2 , Dexton Antony Johns  3 , Vasundara Yayathi Shivashankar  3 , S Sudha  2 , Sujatha Varma  2
Affiliations

Reactive hyperplasic lesions of the oral cavity: A survey of 295 cases at a Tertiary Health Institution in Kerala

S Vidyanath et al. J Oral Maxillofac Pathol. 2015 Sep-Dec.

Abstract

Background: The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at a Tertiary Health Institution in Kerala and compare these data with those of previously reported studies.

Materials and methods: The patient case files from the Department of Oral and Maxillofacial Pathology during the period between January 2007 and December 2011 were reviewed for cases of RHLs of the oral cavity. Both clinical and histopathological diagnoses of reactive lesions were selected for the study. Data including the type of the lesion, age, gender and the site involved were collected.

Results: From a total of 2753 cases reviewed, 295 histologically diagnosed cases of RHLs were obtained with a prevalence of 10.7%. The data consist of 85 (28.8%) males and 210 (71.2%) females. The most common lesion clinically was traumatic fibroma (69.3%) and histologically fibrous hyperplasia (51.9%). The reactive lesions clinically presented as either sessile (54.9%) or pedunculated (45.1%) lesions.

Conclusion: The clinical features of reactive hyperplasia among our patients were similar to those reported previously with divergence in some analyzed data. The novelty in our study was the correlation between histopathology and clinical features which were not reported in literature until date.

Keywords: Peripheral giant cell granuloma; peripheral ossifying fibroma; pyogenic granuloma; reactive hyperplasic lesions; traumatic fibroma.

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Figures

Figure 1
Figure 1
Photomicrograph of of fibrous hyperplasia demonstrating keratinized epithelium and fibrous connective tissue stroma (H&E stain, x100)
Figure 2
Figure 2
Photomicrograph of angiomatous hyperplasia showing proliferating endothelial cells, congested blood vessels with overlying keratinized epithelium (H&E stain, x100)
Figure 3
Figure 3
Photomicrograph of peripheral ossifying fibroma showing areas of calcification in the fibrous connective tissue stroma (H&E stain, x100)
Figure 4
Figure 4
Photomicrograph of peripheral giant cell granuloma demonstrating giant cells in fibrous connective tissue stroma with overlying epithelium (H&E stain, x100)
Graph 1
Graph 1
Distribution of 295 cases of reactive hyperplastic lesions according to clinical diagnosis (%)
Graph 2
Graph 2
Distribution of 295 cases of reactive hyperplastic lesions according to histopathology (%)
See this image and copyright information in PMC

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