Are herpes virus associated to aggressive periodontitis? A review of literature
- PMID: 26980964
- PMCID: PMC4774289
- DOI: 10.4103/0973-029X.174621
Are herpes virus associated to aggressive periodontitis? A review of literature
Abstract
Periodontal Disease includes a wide variety of infectious entities with various clinical manifestations in the oral cavity and responses to treatment. The determinants of clinical manifestations of periodontal disease include the type of infectious agent, the host immune response and environmental factors. Aggressive periodontitis (AP) is defined as a type of inflammation with specific clinical and laboratory features, which distinguish it from other types of periodontitis, with high incidence rates in a sub-group of individuals. Bacteria have been frequently mentioned as the agent inciting gingival inflammation and tissue destruction that underlies the pathogenesis of periodontitis. However, recent studies, with some controversial results, have suggested that the herpes family of viruses, including CMV and EBV-1 as well as papillomaviruses, HIV, Human T-lymphotropic virus type 1, Torquetenovirus and hepatitis B and C occur with high frequency in active periodontal lesions. There is a lack of information about this disease and the role of herpesviruses in its pathophysiology. This review provides a critical analysis of the scientific evidence linking bacteria and viruses with AP and their potential impact on clinical characteristics, prognosis and therapy.
Keywords: Aggressive periodontitis; herpes viruses; periodontal microorganisms.
Figures
References
-
- Chicago: AAP; 1999. The American Academy of Periodontology. Proceedings of the World Workshop in Clinical Periodontics.
-
- Armitage GA. Diagnosis and classification of periodontal diseases. Periodontol 2000. 2005;9:9–21. - PubMed
-
- Tonetti MS, Mombelli A. Early-onset periodontitis. Ann Periodontol. 1999;4:39–53. - PubMed
-
- Armitage GC, Cullinan MP. Comparison of the clinical features of chronic and aggressive periodontitis. Periodontol 2000. 2010;53:12–27. - PubMed
-
- Armitage GC. Comparison of the microbiological features of chronic and aggressive periodontitis. Periodontol 2000. 2010;53:70–88. - PubMed