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. 1989 Dec;69(4):291-6.

Chemoprophylaxis of trypanosomiasis, due to Trypanosoma (Nannomonas) congolense, in rabbits using a slow release device containing homidium bromide

R De Deken, S Geerts, P Kageruka, F Ceulemans, J Brandt, E Schacht, C Pascucci, C Lootens
  • PMID: 2698124

Chemoprophylaxis of trypanosomiasis, due to Trypanosoma (Nannomonas) congolense, in rabbits using a slow release device containing homidium bromide

R De Deken et al. Ann Soc Belg Med Trop. 1989 Dec.

Abstract

The prophylactic activity of a subcutaneously implanted slow release device, containing homidium bromide, was assessed in rabbits, challenged with different stocks of T. congolense, and compared with the classical treatment of 1 mg homidium bromide/kg b.w. intramuscularly. The prophylactic activity of the intramuscular injection was less than a month, while the slow release device protected the rabbits against seven challenges with T. congolense during a period of more than 300 days.

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