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Case Reports
. 2015 Jul-Dec;5(2):274-6.
doi: 10.4103/2231-0746.175772.

A case of laryngeal leiomyosarcoma and review of the literature

Ömer Tarik Selçuk  1 , Levent Renda  1 , Bekir Erol  2 , Üstün Osma  1 , Hülya Eyigor  1 , Hülya Öztürk  3
Affiliations
Case Reports

A case of laryngeal leiomyosarcoma and review of the literature

Ömer Tarik Selçuk et al. Ann Maxillofac Surg. 2015 Jul-Dec.

Abstract

Leiomyosarcoma (LMS) of the larynx is a very rare malignancy that originates from blood vessel, smooth muscle or from the heterotopic mesenchymal tissue in the larynx. The histological diagnosis of LMS depends on the immunohistochemical investigation. The case is here presented of an 82-year-old man with shortness of breath and hoarseness. Indirect laryngoscopy showed a pedunculated large glottic lesion causing airway obstruction. Direct laryngoscopy was performed and biopsies were taken. From the pathological examination, the diagnosis of LMS was made. This case is presented of laryngeal LMS with the clinical, radiological, and histological findings.

Keywords: Glottis; laryngoscopy; larynx; leiomyosarcoma.

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Figures

Figure 1
Figure 1
(a) Indirect laryngoscopy showed a pedunculated large glottic lesion in the left vocal cord causing airway obstruction. (b) A glottic lesion holding the left vocal cord length-wise without the pedunculated part
Figure 2
Figure 2
Oval-shaped hypodense lesion of the left vocal cord extending to the lumen shown in axial computed tomography sections
Figure 3
Figure 3
(a) Overall appearance of the tumor. H and E, ×20, (b) Panck, ×10. The remaining squamous epithelium covering the surface of the tumor stained Panck positive, tumor Panck negative. (c) Smooth muscle paint, ×4, smooth muscle paint stained leiomyosarcoma and not stained squamous epithelium. pedunculated, shows positive cytoplasmic staining (d) Ki-67, ×40, proliferation index and large number of nuclear staining is seen in large magnification
See this image and copyright information in PMC

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