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Comment
. 2016 Mar 15;44(3):522-524.
doi: 10.1016/j.immuni.2016.03.002.

Chitosan: An Adjuvant with an Unanticipated STING

Nicolas Riteau  1 , Alan Sher  2
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Chitosan: An Adjuvant with an Unanticipated STING

Nicolas Riteau et al. Immunity. .
Free article

Abstract

Adjuvants promote adaptive immunity through the triggering of innate signals that are largely poorly understood. In this issue of Immunity, Lavelle and colleagues describe an unexpected role for the DNA sensing cGAS-STING pathway in the mechanism of action of the Th1 cell-promoting polysaccharide adjuvant chitosan.

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