Comment
doi: 10.1073/pnas.1601976113.
Epub 2016 Mar 16.
A role for iron deficiency in dopaminergic neurodegeneration
Affiliations
- PMID: 26984501
- PMCID: PMC4822629
- DOI: 10.1073/pnas.1601976113
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Comment
A role for iron deficiency in dopaminergic neurodegeneration
Proc Natl Acad Sci U S A.
.
No abstract available
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Tfr1-mediated iron uptake is essential for the function of DA neurons. Various perturbations in gene-expression profile and biochemical and metabolic changes in DA neurons occur, leading to their degenerative demise during iron deficiency.
Comment on
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Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice.Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3428-35. doi: 10.1073/pnas.1519473113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929359 Free PMC article.
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