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. 2016 May;54(5):1395-9.
doi: 10.1128/JCM.00446-16. Epub 2016 Mar 16.

A Universal Culture Medium for Screening Polymyxin-Resistant Gram-Negative Isolates

Patrice Nordmann  1 , Aurélie Jayol  2 , Laurent Poirel  2
Affiliations

A Universal Culture Medium for Screening Polymyxin-Resistant Gram-Negative Isolates

Patrice Nordmann et al. J Clin Microbiol. 2016 May.

Abstract

The colistin-containing SuperPolymyxin medium was developed for screening polymyxin-resistant Gram-negative bacteria. It was evaluated with 88 polymyxin-susceptible or polymyxin-resistant cultured Gram-negative isolates. Its sensitivity and specificity of detection were ca. 100%. The SuperPolymyxin medium is the first screening medium that is able to detect intrinsic and acquired polymyxin-resistant bacteria.

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Figures

FIG 1
FIG 1
Polymyxin-resistant lactose-positive E. coli (A), polymyxin-resistant K. pneumoniae (B), polymyxin-resistant lactose-negative E. coli (C), and a mix of a heavy inoculum of P. mirabilis and a low inoculum of polymyxin-resistant K. pneumoniae (C) growing on the SuperPolymyxin medium.
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