Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016;33(3):230-9.
doi: 10.1159/000444147. Epub 2016 Mar 19.

Effect of Vagus Nerve Injury on the Outcome of Antireflux Surgery: An Extensive Literature Review

Selwyn van Rijn  1 , Yvonne G M Roebroek, Jose M Conchillo, Nicole D Bouvy, Adrian A M Masclee
Affiliations
Free article
Review

Effect of Vagus Nerve Injury on the Outcome of Antireflux Surgery: An Extensive Literature Review

Selwyn van Rijn et al. Dig Surg. 2016.
Free article

Abstract

Background: Vagus nerve injury (VNI) is a feared complication of antireflux surgery (ARS). The impact of VNI on the functional outcomes of ARS has not yet been evaluated systematically. The aim of this review was to evaluate the impact of VNI on functional and clinical outcome of ARS.

Methods: A systematic search was performed until March 2015, using the following online databases: MEDLINE, Embase and the Cochrane Register of Controlled Clinical Trials. Eight studies remained available for assessment. Articles were divided into 2 groups: (a) one with unintended, accidental VNI and (b) one group comparing ARS with and without intended vagotomy.

Results: The prevalence of unintended, accidental VNI ranged from 10 to 42% after ARS. No clear differences were seen in outcome for reflux control between the VNI and vagus nerve intact group. A higher prevalence of diarrhea, nausea and vomiting was observed in the VNI group.

Conclusion: VNI is a feared but neglected complication of ARS. Larger prospective studies that objectively assess vagus nerve integrity before and after ARS are needed.

PubMed Disclaimer