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. 2016 Apr-Jun;47(2):513-7.
doi: 10.1016/j.bjm.2016.01.025. Epub 2016 Mar 2.

Phylogenetic characterization of the first Ungulate tetraparvovirus 2 detected in pigs in Brazil

Carine Kunzler Souza  1 , André Felipe Streck  1 , Karla Ratje Gonçalves  1 , Luciane Dubina Pinto  1 , Ana Paula Ravazzolo  2 , David Emílio Dos Santos Neves de Barcellos  3 , Cláudio Wageck Canal  4
Affiliations

Phylogenetic characterization of the first Ungulate tetraparvovirus 2 detected in pigs in Brazil

Carine Kunzler Souza et al. Braz J Microbiol. 2016 Apr-Jun.

Abstract

Ungulate tetraparvovirus 2 (UTV2), formerly known as porcine hokovirus due to its discovery in Hong Kong, is closely related to a Primate tetraparvovirus (human PARV-4) and Ungulate tetraparvovirus 1 (bovine hokovirus). Until now, UTV2 was detected in European, Asian and North American countries, but its occurrence in Latin America is still unknown. This study describes the first report of UTV2 in Brazil, as well as its phylogenetic characterization. Tissue samples (lymph node, lung, liver, spleen and kidney) of 240 piglets from eight different herds (30 animals each herd) were processed for DNA extraction. UTV2 DNA was detected by PCR and the entire VP1/VP2 gene was sequenced for phylogenetic analysis. All pigs from this study displayed postweaning multisystemic wasting syndrome (PMWS). UTV2 was detected in 55.3% of the samples distributed in the variety of porcine tissues investigated, as well as detected in almost all herds, with one exception. The phylogenetic analysis demonstrated that Brazilian UTV2 sequences were more closely related to sequences from Europe and United States.

Keywords: Detection; Hokovirus; Phylogeny; Porcine; Tetraparvovirus; Ungulate.

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Figures

Fig. 1
Fig. 1
Phylogenetic tree constructed by Bayesian Inference based on complete nucleotide sequences of the VP gene of UTV2. The acronym refers to country of each sequence: BR, Brazil; CH, China; GB, Great Britain; GER, Germany; ROM, Romania; US, United States. All the sequences are represented with the accession number from Genbank. The sequences from this study are marked with a black dot. The trees were statistically evaluated with the posterior probability confidence. An UTV1 sequence (EU200668) was used as outgroup.
See this image and copyright information in PMC

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