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. 2006 Feb;18(1):50-1.
doi: 10.1111/j.0924-2708.2006.00109.x.

Psychosis related to methadone withdrawal

Jesús Cobo  1 , María Mar Ramos  1 , Trinidad Peláez  1 , Gemma García  1 , Frederik Marsal  1
Affiliations

Psychosis related to methadone withdrawal

Jesús Cobo et al. Acta Neuropsychiatr. 2006 Feb.

Abstract

We present two cases of typical psychosis related to methadone withdrawal. The two cases, appearing in the adult age, are not related to previous personal or familiar psychiatric illness and do not show the classical symptoms of methadone withdrawal. The appearance of this type of case is an experience repeated in different groups of researchers. In the line of previous investigators, we propose an alteration of neuromodulation in central opiate-dopamine system.

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